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Surgeons Successfully Complete Second Pig-to-Human Heart Transplant


The Transplant Procedure

A team of surgeons at the University of Maryland, led by Dr. Bartley Griffith, has successfully performed the second-ever pig-to-human heart transplant. The recipient, Lawrence Faucette, a 58-year-old man with terminal heart disease, had been ineligible for a transplant with a human heart due to pre-existing vascular disease and complications with internal bleeding. The pig heart transplant was his only option to survive heart failure.

A New Chance at Life

Faucette’s surgery took place on September 20th, and he is now breathing on his own with the new pig heart functioning well, without the need for mechanical support. Dr. Griffith expresses hope that Faucette will soon be able to return home and spend more time with his loved ones.

Advancements in Xenotransplantation

The first pig-to-human heart transplant occurred in January 2022, but the recipient passed away two months later, possibly due to a pig virus. To prevent a similar outcome, the doctors used more sensitive tests to screen the donor pig’s heart for viruses. The transplant also utilized a pig heart with genetic modifications to reduce the chances of organ rejection. In addition, Faucette is receiving a novel medication that helps block the activation of immune responses.

Promising Solution to Organ Shortage

Xenotransplantation, the transfer of animal organs to humans, shows promise in addressing the shortage of donor organs. In the United States alone, approximately 105,000 people are currently waiting for an organ transplant, and 17 people die each day while waiting. Researchers in the field are optimistic that clinical trials for xenotransplantation will be approved by the US Food and Drug Administration in the coming years.

Conclusion

The successful pig-to-human heart transplant gives hope to patients who are not eligible for traditional organ transplants. It signifies a significant advancement in medicine and provides a potential solution to the urgent need for organ donors.

Topics

  • Transplants
  • Xenotransplantation
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